Official Journal of The Academy of Osseointegration
Autologous Dental Pulp Stem Cells in Periodontal Regeneration: A Case Report
Mario Aimetti, MD, DDS/Francesco Ferrarotti, DDS/Luca Cricenti DDS/Giulia Maria Mariani, DDs/Federica Romano, DDS
PMID: 24956088
DOI: 10.11607/prd.1635
Histologic findings in animal models suggest that the application of dental pulp stem cells (DPSCs) may promote periodontal regeneration in infrabony defects. This case report describes the clinical and radiographic regenerative potential of autologous DPSCs in the treatment of human noncontained intraosseous defects. A chronic periodontitis patient with one vital third molar requiring extraction was surgically treated. The third molar was extracted and used as an autologous DPSCs source to regenerate the infrabony defect on the mandibular right second premolar. At the 1-year examination, the defect was completely filled with bonelike tissue as confirmed through the reentry procedure. (Int J Periodontics Restorative Dent 2014;34(suppl):s27–s33. doi: 10.11607/prd.1991)
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